What happens to pyruvate in the intermediate step between glycolysis and Krebs cycle?
Show Understanding: • In glycolysis, glucose is converted into pyruvate in the cytoplasm
At the end of glycolysis, the following reactions have occurred:
Overview of Glycolysis Understanding: • Glycolysis gives a small net gain of ATP without the use of oxygen
Aerobic Respiration
Anaerobic Respiration (Fermentation)
Anaerobic Respiration (Fermentation) What happens to pyruvate between glycolysis and the Krebs cycle?The transition reaction connects glycolysis to the citric acid (Krebs) cycle. The transition reaction converts the two molecules of the 3-carbon pyruvate from glycolysis (and other pathways) into two molecules of the 2-carbon molecule acetyl Coenzyme A (acetyl-CoA) and 2 molecules of carbon dioxide.
What happens to pyruvate in the intermediate step?Pyruvate is converted into acetyl- coenzyme A, which is the main input for a series of reactions known as the Krebs cycle. Pyruvate is also converted to oxaloacetate by an anaplerotic reaction, which replenishes Krebs cycle intermediates; also, oxaloacetate is used for gluconeogenesis.
What is the intermediate compound between glycolysis and the Krebs cycle?So, the correct option is 'Acetyl CoA.
What does pyruvate convert to in the intermediate steps to enter the citric acid Krebs cycle?In order for pyruvate, the product of glycolysis, to enter the next pathway, it must undergo several changes to become acetyl Coenzyme A (acetyl CoA). Acetyl CoA is a molecule that is further converted to oxaloacetate, which enters the citric acid cycle (Krebs cycle).
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