Health n nature royal jelly đánh giá
Australian by Nature is a wholly Australian owned and operated company supplying beehive products, natural health supplements and complementary medicines to Australia and the world. Established in 1995, it has become one of the market leaders in Australian and New Zealand natural health products. Australian by Nature’s range of royal jelly and propolis products, their Manuka honey (from New Zealand) and Australian floral honeys, as well as their other herbal, marine and land-based products are second to none. Show Product Description: Australian by Nature Pure Fresh Royal Jelly is all natural and is loaded with eight essential amino acids, essential fatty acids, Vitamin B Complex, and other traces of vitamins and minerals. Royal jelly is a nutritious milky secretion produced by worker honey bees. It is thought to be the food of the queen bee, which makes them bigger and live much longer compared to the worker bees. Due to its rich natural bio-chemical structure, it is a good source of energy, can help treat various skin diseases, improves collagen levels for great skin, help boost the immune system, improve vitality and overall health. Active Ingredients: Each soft gel capsule contains equiv. Fresh Royal Jelly 600mg (Equiv. 10-Hydroxy-2-Decenoic Acid 12mg) This Product is Halal Certified Certificate available upon request Serving Suggestion: Take one to two capsules once a day. Always read the label. Consume only as directed. If symptoms persist, seek the advice of a healthcare practitioner. Warning Royal Jelly has been reported to cause severe allergic reactions and in rare cases fatalities, especially in asthma and allergy suffers. Consume Royal Jelly with caution. If an allergic reaction occurs, immediately discontinue use and consult a medical practitioner. Royal jelly is a milk-like secretion of honey bees that is used to feed larvae for 3 days for the worker bees and drones and until full development for the queen. Royal jelly has been used widely as a dietary supplement for its purported health prompting properties. Royal jelly is generally well tolerated and has not been linked to serum aminotransferase elevations during therapy or to instances of clinically apparent liver injury. BackgroundRoyal jelly is a milk-like secretion of honey bees (Apis mellifera) that is used to feed larvae in the honeycomb. Larvae that are to develop into drones (males) or worker bees (infertile females) are fed directly and for 3 days only. Larvae that are to become queens (fertile females) are fed the royal jelly secretions in large amounts and until they are fully developed. Royal jelly is harvested from the individual queen bee cells in honey bee hives and used as an emollient in topical creams as well as a dietary supplement for purported medicinal properties. Royal jelly consists of water, proteins, amino acids, fatty acids, simple carbohydrates, vitamins and minerals. The active component that stimulates and modulates larval development is believed to be a series of “major royal jelly proteins” (MRJP). These MRJP alter DNA methylation resulting in an epigenic, nutritionally-driven change in expression of genes responsible for larva development. Royal jelly is used topically in creams and orally in dietary supplements purported to be beneficial for general health and well being. The bases of these claims have not been substantiated, but in vitro and animal studies suggest that components of royal jelly have antiinflammatory and antioxidant properties. Royal jelly is generally well tolerated without adverse events except for rare allergic reactions particularly in patients with a history of asthma or atopic disease. The hypersensitivity reactions can include urticaria, pruritus, erythema, laryngeal edema, wheezing, chest tightness, hypotension, cardiovascular collapse, and in rare instances death. The reactions arise within minutes of ingestion are most likely due to allergy to one of the major royal jelly proteins. Other names: Jalea Real, Bee Saliva, Honey Bee Milk HepatotoxicityLiver injury attributable to royal jelly has not been reported. In clinical trials of royal jelly as therapy of various conditions, side effects were rarely mentioned and ALT elevations and hepatotoxicity were not reported. Despite availability and widespread use as an alternative therapy, there have been no published reports of royal jelly induced liver injury. Likelihood score: E (unlikely cause of clinically apparent liver injury). Mechanism of InjuryRoyal jelly has many components, but none of them has been shown to be particularly hepatotoxic. PRODUCT INFORMATIONREPRESENTATIVE TRADE NAMES Royal Jelly – Generic DRUG CLASS Herbal and Dietary Supplements CHEMICAL FORMULA AND STRUCTUREDRUGCAS REGISTRY NUMBERMOLECULAR FORMULASTRUCTURERoyal Jelly8031-67-2ApitherapyNot Applicable ANNOTATED BIBLIOGRAPHYReferences updated: May 1, 2022
El-Seedi HR, Eid N, Abd El-Wahed AA, Rateb ME, Afifi HS, Algethami AF, Zhao C, et al. Honey bee products: preclinical and clinical studies of their anti-inflammatory and immunomodulatory properties. Front Nutr. 2022;8:761267. [PMC free article: PMC8762236] [PubMed: 35047540] (Extensive review of the preclinical and clinical studies of honey bee products including royal jelly, beeswax and bee pollen; no mention of adverse event rates or hepatotoxicity). |